DT12 Automatic Dissolution Sampling System

Product Description

The DT12 Automatic Dissolution Sampling System is a high-capacity, fully automated solution designed for dissolution testing of oral solid dosage forms including tablets, capsules, and granules. This system integrates a 12-cup dissolution tester with a smart sampling workstation, offering precise, compliant, and efficient testing for pharmaceutical quality control and R&D applications. 

Compliant with major pharmacopoeias, including the United States Pharmacopoeia, the Guiding Principles for Mechanical Verification of drug Dissolution Meter, Chinese Pharmacopoeia (2020), the DT12 is ideal for regulated environments where consistency, data integrity, and operational efficiency are critical. 

DT12 Dimensions & Customisation 

Designed with flexibility and scalability in mind, the DT12 allows for full 12-cup testing or dual-zone operation (6+6), enabling simultaneous tests under different conditions. 

Customisable features include: 

• Programmable methods for up to 5 dissolution test protocols 

• Interchangeable paddle and basket shafts 

• Automatic solvent volume-based height adjustment 

• Optional accessories for specific pharmacopoeial methods 

• 192-position sampling tray for test tubes and HPLC/UV vials 

• RS232, USB, and Wi-Fi connectivity for data export and remote access 

Technical parameters 

Basket (paddle) axis swing degree	≤ 0.5 mm
Swing range of basket	≤ 1.0 mm
Deviation between rotary rod and dissolution cup shaft	≤ 2.0mm
Speed range	(1-300) RPM
Speed resolution	0.01 RPM
Speed error	≤ ±0.1 RPM
Temperature control range	room temperature to 55.0℃
Temperature resolution	0.01℃
Temperature control accuracy	≤ ±0.1℃
Resolution of temperature measurement in dissolution cups	0.01℃
Temperature control accuracy in dissolution cups	≤ ±0.1℃
Sampling channels	12
Sampling holes	192
Sampling volume	1mL-20mL
Minimum sampling interval	1minute for the first time, and ≥3 minutes for subsequent samples
Sampling consistency
Sampling accuracy
Maximum sampling times

 

Technical index 

	DT12	DT08	DT06
Number of channels	12	8	6
Dissolution cup number	12	8	6
Sampling tray	192 (SC12)	128 bits (SC08)	x
Sampling times	1- 16 (SC12/08)	1- 16 (SC12/08)	1- 16 (SC12/08)
Split Paddle Shaft	√	√	√
Water tank lighting system	√	√	√
Water level monitoring	√	√	√
Overheat protection	√	√	√
UV sterilization of water tank	√	√	√
Synchronous dosing/manual dosing	√	√	√
Preheating	√	√	√
7-inch color touch screen	√	√	√
Audit Trail	√	√	√
Multi-level account management	√	√	√
Multifunctional sampling rack	√	√	x
Printer	√	√	x
Fingerprint unlocking	√	√	x
Temperature measurement in each cup	√	√	x
External isothermal rehydration cup	√	√	x
Speed adjustment in different zone	√	√	x

Key Properties of the DT12 System 

The DT12 features advanced automation, intelligent diagnostics, and secure data handling to streamline your dissolution workflow: 

• Automated dosing, sampling, rehydration, and dilution 

• 12-channel sampling system with high-precision syringes 

• Independent temperature monitoring in each cup 

• Built-in sterilisation system and water level monitoring 

• Touchscreen control with Android OS 

• Fingerprint access, password lock, and audit trail for 21 CFR Part 11 alignment 

• Real-time fault alerts and self-diagnostics 

 Applications of the DT12 Dissolution System 

Ideal for large-volume and high-throughput environments, the DT12 is commonly used in: 

• Pharmaceutical manufacturing QC labs 

• Formulation and development facilities 

• University and academic research settings 

• Government and regulatory inspection labs 

It is especially effective for teams needing parallel testing of multiple formulations or conditions. 

 Work with Leading Dissolution Testing Equipment Suppliers in Australia 

M-Kube is proud to distribute Hanon’s DT12 system in Australia, offering end-to-end support from configuration to post-installation. We work closely with QA/QC teams, scientists, and lab managers to ensure smooth implementation and compliance. 

Why choose M-Kube: 

• Local service and technical support 

• Training and validation assistance 

• Fast lead times and reliable spare parts access 

• Custom configurations to meet unique protocols 

 Trusted by Industries Worldwide – Your Global Partner in Analytical Precision 

The DT12 is trusted globally by pharmaceutical companies, CROs, and academic institutions. Backed by        M-Kube’s local support, you gain the advantage of international-grade instrumentation with responsive Australian service. 

✅ Strong Call to Action (CTA): 

Need a high-capacity dissolution testing system in Australia?
Call us on +61478594746 or email info@mkube.com.au to request a quote or more queries.
The DT12 delivers automation, compliance, and performance — all in one system.